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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
27.58
Human Site:
T525
Identified Species:
50.56
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
T525
W
Q
E
E
M
I
E
T
G
I
F
G
E
L
N
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
D492
V
V
K
G
I
Y
L
D
T
A
D
E
D
F
Y
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
E291
E
E
N
P
G
F
P
E
P
R
A
V
F
Y
T
Dog
Lupus familis
XP_542675
460
51324
V423
E
E
M
I
E
T
G
V
F
A
E
L
N
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
T525
W
Q
E
E
M
I
E
T
G
L
F
G
D
L
N
Rat
Rattus norvegicus
Q63651
564
63750
T525
W
Q
E
E
M
I
E
T
G
F
F
G
D
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
T525
W
Q
E
E
M
I
E
T
G
I
F
G
K
L
N
Chicken
Gallus gallus
NP_990026
593
64642
T554
W
Q
E
E
L
I
E
T
G
L
F
D
E
L
N
Frog
Xenopus laevis
NP_001087513
575
66421
T518
W
Q
N
E
I
V
E
T
D
C
F
W
D
L
S
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
V396
P
E
F
T
D
E
P
V
P
N
S
I
G
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
T646
W
Q
N
E
M
M
E
T
E
C
F
R
E
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
T549
W
Q
S
E
M
I
E
T
E
C
F
A
E
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
P771
G
S
F
I
P
G
N
P
N
L
P
P
D
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
0
0
0
N.A.
86.6
86.6
N.A.
93.3
80
46.6
0
N.A.
66.6
N.A.
73.3
N.A.
P-Site Similarity:
100
20
6.6
13.3
N.A.
100
93.3
N.A.
100
93.3
73.3
13.3
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
16
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
24
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
8
8
0
8
8
39
0
8
% D
% Glu:
16
24
39
62
8
8
62
8
16
0
8
8
31
8
0
% E
% Phe:
0
0
16
0
0
8
0
0
8
8
62
0
8
8
0
% F
% Gly:
8
0
0
8
8
8
8
0
39
0
0
31
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
16
47
0
0
0
16
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
8
0
8
0
0
24
0
8
0
62
0
% L
% Met:
0
0
8
0
47
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
24
0
0
0
8
0
8
8
0
0
8
0
54
% N
% Pro:
8
0
0
8
8
0
16
8
16
0
8
8
0
0
0
% P
% Gln:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
16
% S
% Thr:
0
0
0
8
0
8
0
62
8
0
0
0
0
0
8
% T
% Val:
8
8
0
0
0
8
0
16
0
0
0
8
0
8
0
% V
% Trp:
62
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _